cattleprodder
(Hive Bee) 05-14-03 12:09 No 433155 |
oil of mugwort | Bookmark | ||||||
Does anyone know off hand the percent composition of 3,5-dimethoxy-1-allylbenzene in the somewhat expensive but nevertheless commercially available oil of mugwort? Shulgin makes a passing reference to the presence of the aforementioned essential oil under the Essential Spice Oil discussion in Pihkal (under TMA), saying that the oil itself is a reputed stimulant and opiate poisoning antidote according to traditional folklore. I can only imagine what 3,5-dimethoxyamphetamine would be like, but I must admit to being a 1,3,5 / 2,4,6 120 degree bond angle trisubstitution pattern junkie as THC and TMA-6 both enthrall me, not unlike Tantalus the fox and his proverbial bunch of flavonoid containing grapes. |
||||||||
cattleprodder (Hive Bee) 05-14-03 12:39 No 433163 |
Was Shulgin wrong? | Bookmark | ||||||
I just did a quick search for the percent composition of the oil of mugwort and it apparently contains alpha and beta thujone as its essential oils. STAY AWAY. Anyway, 3,5-dimethoxybenzaldehyde is only about 70 USD for 10 grams. |
||||||||
phase_dancer (Stranger) 05-14-03 20:09 No 433242 |
I've often wondered about this. | Bookmark | ||||||
I've often wondered about this. Apart from Shulgins mention I've seen nothing on any activity of 3,5 dimethoxy PEA's or amphetamines. Placing fresh mugwort in a pillow makes for amazing dreams. I assume this is mainly due to the thujone |
||||||||
Rhodium (Chief Bee) 05-15-03 03:56 No 433309 |
3,5-Dimethoxyphenethylamine Activity | Bookmark | ||||||
According to J. Org. Chem. 23(12), 1979-1984 (1958) (../rhodium/pdf /activity.of. However, the article do list several other compounds which could be of interest; such as 3,5-Dibromo-4-methoxy-PEA, 3,5-Dimethyl-4-methoxy-PEA and 3,4,5-Trimethyl-PEA. I think the preparation of all these compounds has already been posted here on the Hive. |
||||||||
phase_dancer (Stranger) 05-15-03 19:19 No 433458 |
Interesting read | Bookmark | ||||||
Thanks Rhodium At the dosage used (25mg/kg intramuscular) those compounds may certainly warrant further investigation. After reading GPig2's post on Post 370205 (GPig2: "4-isobutyl-3,5-dimethoxy-PEA = POISON", Serious Chemistry) I wondered whether other 4th position substitutes may have been tried. I don't really understand why the 3,5-methoxy amines would be thought to be µ opioid antagonists, but then again my SAR knowledge is somewhat limited. |
||||||||