suspiria (Stranger)
09-05-03 23:52
No 457375
       codeine syrup extraction  Bookmark   

SWIM just acquired a bottle of guaifenesin/codeine phsophate syrup.  There's 180mL of syrup, with 2mg/mL codeine, bringing us to the grand total of 360mg of codeine in the syrup.  Brand name is Cheratussin AC Syrup.  How would SWIM go about extracting the codeine from this syrup?  Checked TFSE, and the question has been asked, but never answered, as far as I could find. 		 
 
 
 
    OcoteaCymbarum
(Hive Bee)
09-06-03 00:52
No 457387
       What do you intend to do with 360 mg?  Bookmark   

Take it pure?
Transform it? Then wouldnt .36 grams(which you wouldnt probably end-up isolating, products loss) by a little small to work with? 		 
 
 
 
    jsorex
(Hive Bee)
09-16-03 13:02
No 459383
       Release the base from the phosphate.  Bookmark   

Release the base from the phosphate (using NaOH or other base). Use chlorinated solvent such as chloroform to extract. Then use an acid to get it water soluble again and extract with water.
-jsx