09-01-01 22:27
No 209429
While searching nitroethane in the US patent literature I found these patents which look interesting.
4319059 XCH3COOH + NaNO2 --Mg++--> CH3NO2
4431842 ROH + HNO3 --CaCl2--> RNO2
4073798 MDA related compounds (amines and nitro compounds) made from benzaldehydes and nitroalkanes
4015011 Benzaldehyde and nitroalkane synth, Pd reduction, Eph and halo-Eph compounds reduced
4004023 MD-PNPs insecticidal
http://www.geocities.com/dritte123/PSPF.
(Hive Addict)
09-02-01 02:58
No 209462
US4319059 is cool shit. So, obtaining the nitroethane, nitropropane, etc. from the reaction mixture is as easy as crashing it out with dH2O?
I'm going to help all of you cleanse this diseased planet.
(Master Searcher)
09-02-01 18:22
No 209605
I saw a post by Rhodium before on this type of reaction. Alpha-haloalkanoic acids generally aren't OTC, but don't seem to be watched either. Also, lactic acid might be easily converted into its alpha-halo form. The possibilities......
If you're interested in nitroethane.
http://www.geocities.com/dritte123/PSPF.
(Chief Bee)
09-03-01 02:26
No 209717
Yes, right! I didn't think of lactic acid as a precursor, but as you say, it is a good alternative. There is also the reaction (in Org. Syn. f ex) which produces alpha-bromo derivatives of carboxylic acids using PBr3, either as is, or using red P + bromine.
(Hive Addict)
09-03-01 13:56
No 209817
PolytheneSam, do have refs for the rxns from lactic acid-- through to product?
(Wizard Master)
09-05-01 18:45
No 210535
There is also the reaction (in Org. Syn. f ex) which produces alpha-bromo derivatives of carboxylic acids using PBr3, either as is, or using red P + bromine.
Rhodium: Vogel has a many procedures in synthesizing alpha-bromo derivatives of carboxylic acids.
(Master Searcher)
09-05-01 18:57
No 210536
I don't have any references on lactic acid or anything on alpha-halo acids. You might try here. http://www.orgsyn.org/orgsyn/orgsyn/full
This looks interesting, too. http://www.orgsyn.org/orgsyn/prep.asp?pr
http://www.orgsyn.org/prep.asp?prep=cv4p
http://www.geocities.com/dritte123/PSPF.
(Hive Addict)
09-05-01 20:50
No 210574
alpha halo acids
http://www.orgsyn.org/orgsyn/orgsyn/prep