11-29-01 11:27
No 242162
under N2 at -78C when adding Li for about 20 mins then bring to room temp...would have to be ahydrous
NH2-CH3
C6H5-CH(OH)-CH2-CH3
+ (CH3)-C-Li ===>
NH(t-butyl-Li)CH3
C6H5-CH(t-butyl-Li)-CH2CH3
+ Cl-TMS ==>
NH(Si(CH3)3)CH3
C6H5-CH(Si(CH3)3)CH2CH3
+ sat KF ==> :) ??
would tert-butyl-Li swap the OH? ..it should?
The t-butyl-Li will definately attach to the amine and swap with the silane
sat KF will rip of the silanes
any think this would work?
abc123
Dad made whisky and he made it well, cost two dollars....burned like hell......GD
(Hive Bee)
11-30-01 17:10
No 242765
swim is preety sure this would work if t-butyl-Li can replace an hydroxide on a benzillic carbon
would that happen?
Dad made whisky and he made it well, cost two dollars....burned like hell......GD
(Stoni's sexual toy)
11-30-01 19:30
No 242849
> would that happen?
No, unfortunately not. It will produce the Li salt of the benzyl alcohol. The benzylic OH can't be replaced that way.