07-23-02 17:30
No 336142
I am looking inspiration about a easy & scalable benzylamine synthesis.
I think about benzylchoride + NH3. What solvent do I use? Would an NH3(aq.) (or NH4OH) solution work or maybey better NH3 in MeOH in . There will be the problem of multi alkylation, but what about using an excess NH3 and slowly adding benzylchloride, and afterwards a fractional distillation?
(Hive Bee)
07-23-02 17:57
No 336151
Patent US2987548
Dr. Heckyll & Mr. Jive by Men at Work
...tells my tale.
(Official Hive Translator)
07-23-02 19:35
No 336168
The patent above makes use of 'a rocking bomb autoclave', although says that 60 C and above is sufficient.
Patent US2608584 (referred to by the one Dr_Heckyll posted) uses low temps (5-50 C), but sucks volumetrically - 1 liter of aq. NH3/ether per 43 g of the product (the yield from BzCl - 60%).
How about this Patent GB619827 - looks the best thus far.
Antoncho
(Hive Bee)
07-23-02 20:37
No 336185
Dr_Heckyll, thanks for that ref. The procedure from US patent 2608584 (example 1) is exactly what I had in mind.
Antoncho, the decomposition of benzyl urea looks very nice, very nice indeed
Is benzylamine a suspicious compound to buy?
(Hive Bee)
07-24-02 02:49
No 336293
Even NaCl is a suspicious compound to buy if you walk in the store and say: "Hands up! I want some table salt!" But as there is no commonly known abusable/illegal/controlled/explosive/po
Sorry, Cyrax, didn't mean it personal, didn't mean to make fun of you, but couldn't help it either in the frame of mind I'm in right now, after a bottle of good wine and a lack of good sleep in this full moon night. Good night.
Dr. Heckyll & Mr. Jive by Men at Work
...tells my tale.