Megatherium (Hive Bee) 05-17-03 18:35 No 433727 |
Robinson-Schöpf reaction: tropinone (Rated as: Good references!) |
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Here are a few refs. for the Robinson-Schöpf reaction, involving the synthesis of tropinones from a dialdehyde, methylamine and acetonedicarboxylic acid: R. Robinson, J. Chem. Soc. (1917) vol 111, p 762, 876 C. Schöpf, Angew. Chem. (1937) vol. 50, p 779, 797 K. Alder et al., Ann. (1956) vol. 601, p 147 R. D. Guthrie, J. F. McCarthy, J. Chem. Soc. (1967), p 62 R. V. Stevens, A. W. M. Lee, J. Am. Chem. Soc. (1979) vol. 101, p 7032 M. Langlois et al., Synth. Commun. (1992) vol 22, p 3115 T. Jarevang et al., Acta Chem. Scand. (1998) vol 52, p 1350 Mechanism: http://holivo.pharmacy.uiowa.edu/reactio The synthesis of acetonedicarboxylic acid from citric acid can be found in Organic Syntheses, CV 1, 10 |
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