Vibrating_Lights (Hive Addict)
07-18-03 00:33
No 448113
      Methoxy to Bromine  Bookmark   

Is it possible to convert a methoxy group to a bromide.  Perhaps through a -OH. 

I guess exactly what i'm looking for is a procedure to convert anethol to 4BrPropenylbenzene. 

Could the bromide be converted to the flouride with NaFL in a finkelstien type swap??

Start thinking more like a chemist and less like a criminal
 
 
 
 
    yellium
(I'm Yust a Typo)
07-18-03 00:44
No 448114
      If you're in a lab where you have the chems to  Bookmark   

If you're in a lab where you have the chems to think about such things, it's much easier to order 4-fluorobenzaldehyde.

If you're not in such a lab, thinking about things like this is much like daydreaming.
 
 
 
 
    Rhodium
(Chief Bee)
07-18-03 00:59
No 448118
      Nucleophilic Aromatic Substitution  Bookmark   

The only way to convert aromatic methoxy or hydroxy groups is through Nucleophilic Aromatic Substitution, but the reaction conditions are way too harsh for a substrate like anethole to survive, see the following tutorial for details on Nucleophilic Aromatic Substitution (http://www.people.virginia.edu/~fac6q/242_23_05_06.pdf)
 
 
 
 
    Vibrating_Lights
(Hive Addict)
07-20-03 21:21
No 448680
      daydreaming  Bookmark   

Sometimes day dreaming is all it takes. A day dream is reailty. WIth a flick of a switch and a wave of a hand....then there was.

And cause anethol is much easier to aquire in bulk for swim, And the people who sell these benzyaldehydes are hard to motivate

VL_

Start thinking more like a chemist and less like a criminal