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dildoque
(Newbee) 05-05-01 08:35 No 189419 |
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Hydroquinone | Bookmark | |||||
Is there a simple way from 2-alkyl-phenol to 2-alkyl-1,4-dihydroxybenzene ? NO2->NH2->OH or Br->OH ??? |
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Rhodium (Chief Bee) 05-05-01 10:26 No 189443 |
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Re: Hydroquinone | Bookmark | |||||
Both are possibilities, but I would think that the latter alternative would be better. The first one will produce a lot of o-nitrated phenol. Use a bulky brominating agent, and the para-selectivity will be good. Then reflux the bromide with Cu powder in a KOH solution to get the hydroquinone. Another method would be to formylate the phenol in the para position, and then oxidize the aldehyde to the phenol using bayer-villiger conditions. http://rhodium.lycaeum.org |
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