Skindeep_Assrash
(Hive Bee) 08-19-01 08:41 No 205785 |
Subbing Tert with MeOH & Pd(AcO)2 with PdCl2 ? | Bookmark | ||||||
SWISA needs to know if this recipe has anything wrong with it. READ CAREFULLY: To a 5L 2-neck flask equipped with condendor and addition funnel goes: -100gm safrol -5gm Palladium Chloride -250ml methanol Commence with the magnetic stirring full bore while bringing temp to 80c. -over 30 minutes time frame,start adding H2O2 when temp reaches 78-80C. Maintain reflux at 78-82C for a TOTAL of 6 hours. Flood with dH2O and clean up with solvent (DCM, toluene, etc) The original synthesis was found in TSII but used Tert-butyl alcohol instead of MeOH and Palladium acetate instead of Palladium Chloride. Are these modifications realistic if one wants to yield the precoius oil (smells to ketone)? Assrash Ouch! |
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terbium (Hive Addict) 08-19-01 08:57 No 205789 |
Re: Subbing Tert with MeOH & Pd(AcO)2 with PdCl2 ? | Bookmark | ||||||
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Osmium (Stoni's sexual toy) 08-19-01 15:34 No 205820 |
Re: Subbing Tert with MeOH & Pd(AcO)2 with PdCl2 ? | Bookmark | ||||||
Besides, the tert-BuOH thing doesn't work. |
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sunlight (Hive Bee) 08-19-01 18:16 No 205845 |
Re: Subbing Tert with MeOH & Pd(AcO)2 with PdCl2 ? | Bookmark | ||||||
Noone have get something interesting with it. I remember some test with methanol and didn't work. |
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