Vaaguh (Stranger)
12-18-02 16:14
No 390625
       ppa from propenylbenzenes: on using methylstyrene  Bookmark   

To my best knowledge propenylbenzene is also named methylstyrene, is methylstyrene (mixture of 3- and 4- isomer) the correct reagent to be used for the synthesis of Phenylpropanolamine? 		 
 
 
 
    Rhodium
(Chief Bee)
12-18-02 17:06
No 390644
       Methylstyrene doesn't come in any 3- or ...  Bookmark   

Methylstyrene doesn't come in any 3- or 4-isomers.

beta-Methylstyrene is the same thing as Propenylbenzene, and this in turn comes in cis- and trans-form, any which is good for PPA synthesis.

alpha-Methylstyrene is another thing altogether, and cannot be used. 		 
 
 
 
    Vaaguh
(Stranger)
12-18-02 17:55
No 390657
       from the merck catalogue:  Bookmark   

METHYLSTYRENE (MIXTURE OF 3-AND 4-ISOMER   MERC8.22098.1000

This is directly copied from a merck catalogue, is it correct to asume this reagent is of no use for the synthesis of PPA ?

  
 
 
 
    terbium
(Old P2P Cook)
12-18-02 19:27
No 390685
       Methyl on the ring.  Bookmark   

is it correct to asume this reagent is of no use for the synthesis of PPA ?
That would seem to be a correct assumption.

Baseline Does Not Exist.