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indole
(Hive Bee) 08-09-01 04:07 No 202678 |
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methyl-PA, methyl-DOPA, -> amp, mda? | Bookmark | |||||
I UTFSE and could not find anything specifically along these lines: Can the boiling decarboxylation used to go from tryptophan to tryptamine be used to go from PA to phenylethylamine? If so: Could alpha-methyl-PA be decarboxylated to amp? AND could alpha-methyl-DOPA be decarboxylated to 3,4-dihydroxy-amp, and easily be methylenated(sp) to mda? amines to an end |
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Rhodium (Chief Bee) 08-09-01 11:58 No 202747 |
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Re: methyl-PA, methyl-DOPA, -> amp, mda? | Bookmark | |||||
The answer to the first questions should be yes, and I believe there is some info on this at my page. On the third question, I think that the Methyl-DOPA molecule is to fragile to survive a decarboxylation. |
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indole (Hive Bee) 08-09-01 14:39 No 202766 |
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Re: methyl-PA, methyl-DOPA, -> amp, mda? | Bookmark | |||||
Could the methylenation occur prior to the decarboxylation? If so, would that withstand decarboxylation? On another note, Shulgin stated methylenedioxy-phenylethylamine had no effect. Would this be because it was broken down before the blood/brain barrier? If so, MD-PA should pass through and be decarboxylated, like L-DOPA, possibly having action?!?!?! Sorry, I am just so full of questions and so few answers... amines to an end |
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Rhodium (Chief Bee) 08-09-01 15:52 No 202780 |
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Re: methyl-PA, methyl-DOPA, -> amp, mda? | Bookmark | |||||
I believe that the amine group would interfer with a methylenation reaction, so that would be hard. 3,4-MD-PEA is probably very readily broken down by MAO enzymes, and it is also probably of very low potency even if taken with a MAOI. There are reports on my page of 3,4-dimethoxy-PEA being active at 500mg together with a MAOI. |
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