08-15-01 03:52
No 204640
another way to P2P
Letts Nitrile synthesis: ref: chem rev. 42, 264 (1948)
RCOOH + KSCN -heat-> RCN + KHS + CO2
use phenylacetic acid to get it's respective nitrile- or obtain it by other measures.
now you have the nitrile.
nitrile + MeMgBr --> imine --acid--> P2P
(Chief Bee)
08-15-01 11:56
No 204737
Can R be aromatic as well as aliphatic?
(Hive Addict)
08-15-01 16:36
No 204769
that obit hasn't figured out yet, definitely aliphatic, maybe aromatic. can't seem to find anything other than that one reference. haven't had time to look up the actual ref yet either. if somebody would search for some info on it, obit would be greatly appreciative. (P-Sam, master searcher, please)