bottleneck
(Newbee) 08-23-02 12:05 No 348066 |
Allylbenzene to amphetamine with lithium amides | Bookmark | ||||||
Hi, I don't know if everybody knows about this already. In the articles they made a lithium amide from n-BuLi and an amine, and react it with an allylbenzene in a pressure-reactor. Hartung et al. "A Base-Catalyzed Domino-Isomerization-Hydroamination Reaction - A New Synthetic Route to Amphetamines." Tetrahedron vol. 56, no. 29, 14. July 2000, pp. 5157-62 DOI:10.1016/S0040-4020(00)00436-1 Post 465442 (Rhodium: "Hydroamination Route to Amphetamines", Chemistry Discourse) Seijas et al. "Synthesis of beta-Phenylethylamines from Styrene Derivatives." Tetrahedron Letters, vol. 39, no. 28, 9. July 1998, pp. 5073-6 DOI:10.1016/S0040-4039(98)00907-1 Post 465452 (Rhodium: "beta-Phenylethylamines From Styrenes", Chemistry Discourse) Beller et al. "Base-Catalyzed Hydroamination of Aromatic Olefins - An Efficient Route to 1-Aryl-4-(arylethyl)piperazines." Tetrahedron vol. 54, no. 23, 4. June 1998, pp. 6359-68 DOI:10.1016/S0040-4020(98)00295-6 |
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