![]() |
![]() |
|||||||
Rhodium (Chief Bee) 03-23-03 16:26 No 420645 |
![]() |
2,5-MeO-PhCOMe, PhCH2COOH, -CHO & - CH2OH (Rated as: excellent) |
Bookmark | |||||
This is largely a post made by PolytheneSam, with minor edits by me and addition of the Chem Ber article /Rhodium Synthesis of alliodorin dimethyl ether Indian Journal of Chemistry, Section B, 15B(11), 988-90 (1977) (../rhodium/djvu /alliodorin. Abstract Alliodorin di-Me ether (I) was prepd. in 10 steps from 2,5-(MeO)2C6H3COMe via Willgerodt reaction, redn., oxidn., Grignard reaction, Claisen rearrangement, Wittig reaction, etc. Preparation of 2,5 dimethoxy phenylacetic acid, 2,5 dimethoxy phenylacetaldehyde and 2,5 dimethoxy phenyl ethanol. Note on page 989 under Experimental Procedure: 2,5-Dimethoxyacetophenone (II) -- It was prepared from dimethoxybenzene and acetyl chloride in the presence of anhyd. aluminium chloride according to the procedure described in literature5 Reference 5 is Chem Ber 38, 789 (1905) (../rhodium/25-dimethoxyacet Could you use chloroacetone in place of acetyl chloride to get 2,5-DimethoxyP2P? There seems to be a contradiction here Post 346121 (Vibrating_Lights: "AlCl3 and Md compounds", Chemistry Discourse) See also Post 255616 (PolytheneSam: "Re: Substituted P2P's: Would this work?", Novel Discourse) Post 255661 (PolytheneSam: "Re: Substituted P2P's: Would this work?", Novel Discourse) |
||||||||
![]() |
![]() |
|||||||