dormouse
(Member) 04-19-00 14:37 No 122772 |
MDA from Coffee -Wizard X | Bookmark | ||||||
Author Topic: MDA from Coffee Wizard X Moderator posted 11-27-98 09:58 PM ---------------------------------------- " RESISTANCE IS FUTILE - MDA FROM COFFEE " I was looking in my spell book and remembered a dream I had sometime ago. MDA from coffee. Caffeic acid ( 3,4 - dihydroxycinnamic acid ) from green coffee (unroasted ) contains about 6% total Caffeic acid and Chlorogenic acid ( hydrolysis of chlorogenic acid gives caffeic acid ). It is also found in roasted coffee. Isolation from green coffee beans , J. Agr. Food. Chem Vol 8 , pg 58 (1960) & roasted coffee , Arch. Pharm. Vol 293 , pg 721 (1960). One kilo of ground coffee beans yields approx 50 - 55 grams of caffeic acid . Both caffeic acid and caffeine are freely soluble in boiling water. Also methyamine has been seriously dreamed from caffeine , that for another time. METHYLENE DIOXYCINNAMIC ACID METHYL ESTER - MDCAME [ 1 ] Generate the Caffeic acid Methyl Ester as this stops the coupling together of the caffeic acids with I-CH2-I at the -COOH MDA SYNTHESIS From MDCAME via Piperonal & Nitroethane - 4 steps. Directly from MDCAME - 5 steps. Step 3 , Reduction of the nitropropenyl to an amino , ( -CH2- NH2 ) and the methyl ester to an hydroxy ( -OH ) Step 4 , Reaction with Tosyl chloride ( Tolulene-p-sulphonyl chloride ) on the OH & NH2 Step 5 , Reduction of the sulphonate ester and the sulphonate amide to give MDA |
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