08-18-03 17:01
No 454359
Arylalkylamine Drugs of Abuse: An Overview of Drug Discrimination Studies
Richard A. Glennon
Pharmacology Biochemistry and Behavior, Vol. 64, No. 2, pp. 251–256 (1999) (../rhodium/pdf /glennon.aryl
DOI:10.1016/S0091-3057(99)00045-3
Abstract
Abused arylalkylamines fall into two major categories: the indolealkylamines, and the phenylalkylamines: These agents can be further subclassified on the basis of chemical structure. Examples of these agents possess hallucinogenic, stimulant, and other actions. Drug-discrimination techniques have been used to classify and investigate this large family of agents. Such studies have allowed the formulation of structure–activity relationships and investigations of mechanisms of action. Arylalkylamine designer drugs also possess the same or a combination of actions, and are being investigated by the same methods.
