psyloxy ( )
04-01-00 14:56
No 126879
      AMT and AET from Tryptophan and electrolysis  Bookmark   

I know that some of you don't like electro-cheistry. Well I'm sowewhat a fan of it. However I still don't have an electrolysis-cell but what they make possible is great.

So let's go for AMT and AET from Tryptophan with the help of electrochemistry.

AMT

Tryptophan + SOCl2 --> tryptamin-C(=O)Cl
tryptamin-C(=O)Cl + electr. --> AMT

Or:

Tryptophan --> Indol-3-acetaldehyd
(see Rhodiums site for this one)

Indol-3-acetaldehyd + CH3NO2 --> [uhm well how is this called ?]

[uhm well how is this called ?] + eC --> AMT

AET

Indol-3-acetaldehyd + CH3-CH2-NO2 --> [indol-nitrobutene ?]

[indol-nitrobutene ?] + eC --> AET

Or:

Tryptophan + eC --> Tryptamin-CH2-OH [not sure]

Tryptamin-CH2-OH + SOCl2 --> Tryptamin-CH2-Cl

Tryptamin-CH2-Cl + BrMg-CH3 --> AET

So are these speculations worth shit or more ?

--psyloxy--