![]() |
![]() |
|||||||
pHarmacist (Hive Addict) 03-23-03 15:30 No 420430 |
![]() |
2-Substituted Tryptamines; [...] (Rated as: excellent) |
Bookmark | |||||
[...] Agents with Selectivity for 5-HT6 Serotonin Receptors J. Med. Chem.; (Article); 2000; 43(5); 1011-1018 Jason E. Savage, Ace McBride, Laura Rauser, Sandy Hufeisen, and David K. H. Lee§ Departments of Biochemistry, Psychiatry, and Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, and Allelix Biopharmaceuticals, Mississauga, Ontario L4V 1V7, Canada Abstract: Several 2-alkyl-5-methoxytryptamine analogues were designed and prepared as potential 5-HT6 serotonin agonists. It was found that 5-HT6 receptors accommodate small alkyl substituents at the indole 2-position and that the resulting compounds can bind with affinities comparable to that of serotonin. In particular, 2-ethyl-5-methoxy-N,N-dimethyltryptamine Full-text: http://pharmacist8.tripod.com/2-subst-tr Accept No Imitations, There Can Only Bee One; www.the-hive.ws |
||||||||
![]() |
![]() |
|||||||