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Rhodium (Chief Bee) 08-04-03 16:41 No 451691 |
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One-pot synthesis of Tryptophols & Tryptamines (Rated as: good read) |
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Tandem Hydroformylation/Fischer Indole Synthesis: A Novel and Convenient Approach to Indoles from Olefins Petra Köhling, Axel M. Schmidt, and Peter Eilbracht DOI:10.1021/ol0350184 ![]() Abstract A novel one-pot synthesis of indole systems via tandem hydroformylation/Fischer indole synthesis starting from olefins and arylhydrazines is described. This tandem procedure leads directly to 3-substituted indoles if unsubstituted phenylhydrazine is used and to 3,5- respectively 3,7-disubstituted indoles if para- or ortho-substituted arylhydrazines are used. |
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