08-15-01 16:31
No 204926
Does anyone know if there is any scope for the developement of new drugs using solid phase chemistry. I was thinking of anchoring the basic amphetamine subunit to the solid phase using a linker known as the 'bromo WANG' linker. Basically just a resin bound benzylbromide. I have a bit of experience with solid phase organic chemistry. I have been playing with this idea for a little while now and I was wondering if it has any worth. Could a whole new library of say amphetamine type drugs be built up this way??
(Hive Addict)
08-17-01 19:13
No 205547
General Combinatorial Synthesis of Tertiary Amines on Solid Support.
Tetrahedron letters
42 (2001) 133-136
This is more applicable to some tryptamine goodies.
Do Your Part To Win The War