Flip (Hive Bee)
08-12-02 21:11
No 344962
      MP-NEt3BH4 in place of NaBH4 for reductions  Bookmark   

Is there any reason that one could not use macroporous triethylammonium methylpolystyrene borohydride in place of NaBH4 for reductive amination?

I'm sure the DEA would rather skip it than waste an entire breath asking me why the fuck I would order macroporous triethylammonium methylpolystyrene borohydride

http://www.argotech.com/PDF/resins/mp_borohydride.pdf


"I like you, but I wouldn't want to see you working with subatomic particles."
 
 
 
 
    terbium
(Old P2P Cook)
08-12-02 22:45
No 344982
      Should work fine.  Bookmark   

This product should work fine for the reduction of methylimines. The only negative is that it is bulky - about 300 grams per mole of BH4.
 
 
 
 
    Flip
(Hive Bee)
08-12-02 23:20
No 344992
      Re: 'Should work fine.'  Bookmark   

Thanks,
I suspected as much but I am never 100% with anything for lack of an official education.  Been dreaming on reductions and borohydride substitutes came to mind.  I know this one is a little obscure.  I'm learning though.  I'm not sure how much this shit costs but even an inconvienient substitute is a good one, and sometimes a good precaution, when your own name is on the order form.

Flip

"I like you, but I wouldn't want to see you working with subatomic particles."