java (Hive Bee) 08-06-04 04:23 No 523922				Nitriles and Ketones from primary amines..... (Rated as: excellent)
						An Insight of the Reactions of Amines with Trichloroisocyanuric Acid Lidia De Luca,* Giampaolo Giacomelli* SYNLETT 2004, No. x, pp 000A–000Ex. Abstract: The reaction between amines or a-aminoacids with trichloroisocyanuric acid is studied under various conditions: N,Ndichloroamines, nitriles and ketones can be obtained from primary amines, while free aminoacids undergo oxidative decarboxylation to the corresponding nitrile of one less carbon atom. Conclusion  this work has shown an easy transformation of amines and a-aminoacids through reaction withTCCA: in all cases the yields are practically quantitative and the products recovered in pure form from the reactionmixture.21 This method is characterized by mild reaction conditions, non-toxic by-products and easy reaction work-up, making it ideal for both laboratory and large scale. Edit by Java... It is worth pointing out that if one was to start with phenylalanine one can make the 2-phenylacetonitrile and using the same material TCCA one can also make the methylamine from another amino acid.......... Just hold on to the thread...that keeps us going http://www.chiapaslink.ukgateway.net/