RepVip (Hive Bee)
08-26-04 04:45
No 527395
      Benzylamphetamine (benzphetamine)     

Would like to inquire if anybee has bioassayed benzylamphetamine (as is spelled on the LG bottle in swims lab, but is more commonly known as benzphetamine, under the prescription brand Didrex) ?

Swim was google'ing for toxicity information but has not found much, other than benzphetamine having negative reproductive effects. More curious to see toxicity as compared to amphetamine or methamphetamine.

Swim has tried a minute amount in a "taste test" and had a bad experience. The compound had an extremely bad taste and burning sensation, which lasted for at least 20 minutes. Nothing like amphetamine/methamphetamine. Nothing.

So what about the intragastric route?
http://userwww.sfsu.edu/~cberkman/640_notes_1.4.pdf (http://userwww.sfsu.edu/~cberkman/640_notes_1.4.pdf)
At the bottom of page 3 has a proposed phase 1 metabolism of benzphetamine. Do the metabolites appear to be active? A better question is, Are the proposed metabolites likely to occur?

Any thoughts on the matter would be great.. maybe from somebee that has used Didrex? Swim imagines there is only one practicle route to use this drug. The only question in swims mind now is, is it too toxic?

Thanks,
RV
 
 
 
 
    java
(Hive Addict)
08-26-04 17:38
No 527510
      Clinincal Research on Benzphetamine.....     

You might want to check this out for some information you're seeking.......


http://amphetamines.com/benzphetamine


saludos,.....java

It is better to die on your feet than to live on your knees.......
-Emiliano Zapata-
 
 
 
 
    Nicodem
(Hive Bee)
08-26-04 21:40
No 527546
      Sorry for being slightly off topic, but isn't...     

Sorry for being slightly off topic, but isn't it a waste of material eating that when it can be nicely N-methylated with formaldehide and formic acid (classical Leuckart-Wallach) and debenzylated with H2/Pd-C?

“The real drug-problem is that we need more and better drugs.” – J. Ott
 
 
 
 
    RepVip
(Hive Bee)
08-29-04 21:28
No 528139
      No.     

Actually, I consider it a complete waste of time trying to N-methylate with formaldehyde and secondly de-benzylate with hydrogenation--especially when you only have <1 gram to work with. That is fucking pointless.

What do you expect? You think anybody would have more of this kind of drug? Not likely. Did you even look at the proposed metabolic pathway?

You know, all I wanted was to find a little toxicology information, and instead you engage autopilot and shout out your off-topic opinion, just like all the other lurkers at The Hive do, trying to act smart and put otherbee's down for no fucking reason.

To Java:
Thanks for the link.
 
 
 
 
    RepVip
(Hive Bee)
08-29-04 21:35
No 528141
      More Info     

Somewhat generic, but more info on this "proamphetamine" can be found here. (http://www.inchem.org/documents/pims/pharm/pim061.htm)