Bwiti
(Hive Addict) 10-03-01 10:36 No 219895 |
Reduction of P2Ps - From T.S.2, method 7 | Bookmark | ||||||
Why not replace the sodium amalgam with Al/Hg made from something less suspicious than mercuric chloride like mercuric nitrate? Wouldn't one get better yields than with the more common Al/Hg reduction that doesn't use hydroxylamine? Peace! I'm going to help all of you cleanse this diseased planet. |
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hypo (Hive Bee) 10-03-01 11:20 No 219912 |
Re: Reduction of P2Ps - From T.S.2, method 7 | Bookmark | ||||||
don't understand question, but Al/Hg reduction of P2P-ketoximes has been brought to work (allthough yields are not enormous): Post 189985 (Antibody2: "Re: MDA via oxime", Methods Discourse) |
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Bwiti (Hive Addict) 10-03-01 14:00 No 219964 |
Re: Reduction of P2Ps - From T.S.2, method 7 | Bookmark | ||||||
"10% aqeous MeOH with 4 equiv HOAc (w/ lewis acid *) 62%!!!" That's not too bad, because it's not that exothermic and MDOH is active. I'm guessing this could be easily scaled up, but it requires more chemicals than one would need to do a reduction of a plain old p2p. I'm thinking that one would have more "luck" with the more common p2p reduction, because there's more literature covering it. Maybe I should search patents for zinc-amalgam reductions? I was just wondering what options an evil chemist has for reductions. Thanks for that link! How about using borohydride/nickel boride on a ketoxime? Peace! I'm going to help all of you cleanse this diseased planet. |
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hypo (Hive Bee) 10-04-01 11:14 No 220297 |
Re: Reduction of P2Ps - From T.S.2, method 7 | Bookmark | ||||||
no idea about borohydride/Ni. but according to this little treasure i found on rhodium's, urushibara should work: ../rhodium /znhg.al
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