Barium (Hive Bee) 01-10-03 14:08 No 396934				Aromatic iodination of phenylpropanolamines	Bookmark
						p-OH-norepedrine and p-OH-ephedrine is iodinated with ethanolic solutions of iodine. Patent GB1040736 Catalytic hydrogenation freak
		Rhodium (Chief Bee) 01-10-03 15:50 No 396942				Patent Text	Bookmark
						British Patent 1,040,736 EXAMPLE 1 2.3 g of para-hydroxynorephedrine are dissolved in 5 ml of water to which are added 25 ml of NH4OH (d=0.90). A solution of 5.78 g of iodine in 50 ml of 95% ethanol is added, while stirring, over a period of 45 min. The formed 1-(4-hydroxy-3,5-diiodo-phenyl)-2-aminopropanol becomes insoluble in the course of the reaction. The precipitate, separated out by filtration, is washed with cold distilled water and then purified by dissolving it in a sodium hydroxide solution followed by precipitation by means of a current of CO2 to give the product in the form of the free base, mp 212°C. EXAMPLE 2 4.35 g (20 millimoles) of para-hydroxyephedrine hydrochloride are dissolved in 50 ml of distilled water to which 140 ml of NH4OH are added (d=0.90). A solution of 11.43 g (90 millimoles) of iodine in 150 ml of 95% ethanol is added, while stirring, over a period of time of 45 min. The 1-(4-hydroxy-3,5-diiodophenyl)-2-(methylamino)-propanol becomes insoluble in the course of the reaction. The precipitate, which is separated out by filtration, is washed with cold distilled water and then purified by dissolving it in a sodium hydroxide solution followed by precipitation by means of a current of CO2. mp 186°C.
		Sunlight (Pioneer Researcher) 01-10-03 18:02 No 396976				amphetamines and phenethylamines	Bookmark
						Any oppinion about if it can work with amphetamines and phenethylamines ?
		Rhodium (Chief Bee) 01-10-03 18:08 No 396978				By all means, it should, as long as it is a...	Bookmark
						By all means, it should, as long as it is a 4-hydroxy derivative. There is no reason to believe that an aliphatic alcohol on the side chain should modify the reactivity at all. Also see Post 285579 (foxy2: "3,5-diiodo-4-methoxyphenethylamine", Chemistry Discourse) for the same reaction performed on tyramine.
		Osmium (Stoni's sexual toy) 01-10-03 19:54 No 397000				> 50 ml of distilled water to which 140 ml...	Bookmark
						> 50 ml of distilled water to which 140 ml of NH4OH are > added (d=0.90). A solution of 11.43 g (90 millimoles) of > iodine in 150 ml of 95% ethanol is added, I'm not sure I want to filter that precipitate... I'm not fat just horizontally disproportionate.
		Aurelius (Hive Addict) 01-10-03 20:43 No 397008				complex	Bookmark
						That complex is stable to a degree warranting only careful consideration of the material.  if you keep in wet with Ammonia solution and dispose of it in a safe place (outside away from anything important) everything should be fine.  let it dry for about an hour outside, then start chucking pebbles at it.  fun stuff.