08-13-03 10:59
No 453287
Swim was wondering when in the process of making MDMA using MDP2P,monomethylamine,platinum oxide and hydrogen in methanol if it is possible to replace the monomethylamine,hcl for trimethylamine,hcl??
(Hive Bee)
08-13-03 11:12
No 453290
Well, you won't get any MDMA for sure. If you where planning on making MDdiMA, that wont work either as trimethylamine is fully substituted and won't react with ketones in the usual manner(or any manner AFAIK)...
Size doesn't matter, it's the sound you make when hitting the ground after smoking it, that matters!
(Stranger)
08-13-03 13:25
No 453296
EXCUSE ME! What i ment was replacing methylamine for triethylamine HCL!
(Hive Bee)
08-13-03 13:36
No 453297
Same principle for triethylamine... Won't work either!
You need either methylamine og nitromethane to make MDMA from MDP2P... Nothing(probably) else will work(for the direct route that is).
The tertiary amines are never used for substitution reactions like that, because the simply don't react that way. All of their available electron sites are taken by the alkyl chain. The only thing left are the lone pair, which you wont get to react :) The tertiary amines are often used as a pseudo-inert base, as they wont react with stuff like methyliodide and the like, but still can scavange for some H+ and make a quatinary salt.
Regards
bandil
Size doesn't matter, it's the sound you make when hitting the ground after smoking it, that matters!
(Newbee)
08-14-03 01:06
No 453425
for tertiary amines to not form imines easily.
What are electron sites? How does monomethylamine have more electron site then triethylamine? Imine formation doesnt involve any electrons from the alkyl groups!
The reason that wont happen is more likely to be because of steric hindrance, which makes the imine formation so slow and hard that it's negligible.
(Hive Addict)
08-14-03 02:19
No 453432
You have a curious explanation for tertiary amines to not form imines easily.
Isn't it just that the tertiary amine has no protons to transfer/donate (whether it's trimethylamine OR triethylamine HCl), necessary for the imine formation, rather than steric hindrance?
(Chief Bee)
08-14-03 02:45
No 453439
Acid_egg has the correct explanation. Even secondary amines doesn't form proper imines with ketones, they rather tend to form enamines...
(Newbee)
08-14-03 05:30
No 453455
I was stone a little earlier and it shows.
I hadn't even though about the proton!
Thanks for correcting me.
I smoke too much weed I guess
(Hive Addict)
08-14-03 19:38
No 453547
Sometimes I wonder what the utility of responding to posts like this one is. I'm not sure that I want to encourage someone like this. I think that some basic understanding of what you are doing is necissary to deliver a safe product to consumers.