09-09-03 22:20
No 457957
Swim searched the posts and couldn't find anything on experiences or successes with producing heroin from MS Contin. He thought that it was probably just as easy to extract it as would be morphine HCl but he doesn't know if the reaction with anhydride will work with the suplfate rather than the HCl salt.
Any suggestions/experiences or tips?
Swim to Deep Space 9
(Hive Bee)
09-09-03 23:05
No 457970
Well contins are filled with oxycodone, are you talking about just extracting this stuff or actually turning it into heroin?
DIY - Do or die
(Hive Addict)
09-10-03 01:30
No 458002
Well contins are filled with oxycodone, are you talking about just extracting this stuff or actually turning it into heroin?
Wrong. MS Contin is Morphine Sulfate. However, OxyContin is OxyCodone.
09-10-03 21:41
(Rated as: insignificant)
09-10-03 23:10
(Rated as: insignificant)
(Newbee)
09-11-03 04:14
No 458278
When extracting those pills, I'd do an A/B anyway, after dissolving in H20 and filtering, to get rid of any non-alkaloid crap. Use HCl to claim the desired alkaloid from the non-polar layer, there you've got your Morph.HCl !
(PVC-Analog Taste-Tester)
09-11-03 09:44
No 458346
I wonder what would be created if oxycodone is refluxed with acetic anhydride?
Love my country, fear my government.
(Chief Bee)
09-12-03 02:31
No 458513
Oxycodone
Reaction of this with acetic anhydride would very likely attach an acetyl group to the free OH group (but it is very sterically hindered, so the yield might not be very good, at least not without the addition of a catalyst like DMAP).
The big question is however if it would be worthwhile to perform the reaction - the free OH group is not phenolic (and thus acidic) like the ones on morphine, so the lipophilicity will not be considerally affected by the acetylation, and it is thus not likely that the potency of the drug will be affected by such a conversion.
(Hive Bee)
10-05-03 19:16
No 462745
What about when you react with Glacial Acetic Acid? Do you use the base or HCl Salt?
"How to Shit Fire" - Secrets of the Habenero
(Distinctive Doe)
10-05-03 19:42
No 462755
What about when you react with Glacial Acetic Acid?
No Acetic ANHYDRIDE.
I would react the acetate salt if I had the choice. This is pure speculation tho.
10-06-03 19:51
(Rated as: incomprehensible)
(Chief Bee)
10-06-03 22:02
No 463029
(Rated as: good read)
The term "junk" is not correct chemical nomenclature for anything. Please stick to generic chemical descriptors.
Possible reactions:
Morphine Freebase + Glacial Acetic Acid -> Morphine Acetate
Morphine Acetate + Acetic Anhydride -> Diacetylmorphine acetate (Heroin acetate)
Morphine Freebase + Acetic Anhydride -> Diacetylmorphine acetate (Heroin acetate)
First, make sure that you have understood the difference described in Post 90174 (Osmium: "Acetic Anhydride vs. Glacial Acetic Acid (GAA)", Chemicals & Equipment)
Then, if you take a look at the article 4-Dimethylaminopyridine as a catalyst in heroin synthesis (../rhodium/pdf /heroin.synth
02-28-04 16:54
(Rated as: insignificant)
(Hive Bee)
03-07-04 02:34
No 493537
Can the morphine sulfate extracted with a normal A/B from MST Cont? For example dissolving the pills in water (Q: should i just wash with handwarm water or should i boil it and remove the waxy product on top after cooling?). Then an A/B followed by toluene extraction, then gas with HCl?
