05-09-04 20:47
No 506132
I was reading a prep on Organic syntheses about a wacker-type of oxidation and the easiness and the yields just seem great
Basically, using 32 grams of CuCl2 and 1.19 grams of PdCl2, the author claims a 78% yield on 1.66 moles of alkene.
The starting compound is 2,2 dimethyl-4-pentenal and the end product the corresponding methylketone.
http://www.orgsyn.org/orgsyn/prep.asp?rx
As anyone ever tried something similar? Imagine the yields being the same for our favorite alkene...
(Hive Bee)
08-12-04 22:45
No 525195
this seems to be fairly easy, but processing time of 60 ro 66 hr is long, isn't it?
oops i did it again
(Hive Bee)
08-13-04 07:01
No 525259
I know I wouldnt.
Using 1.19 grams of Palladium to transform about 270 grams of safrole into 230 grams of ketone, I wouldnt care about those 60 hours.
What I really wonder about is oxygen flow. They dont mention it anywhere, its the drawback I find. So its seems its really a matter of how much oxygen needs to be used.
I had totally forgotten about this post, I realize the title of thread is not right.
(Chief Bee)
08-13-04 09:15
No 525276
Post 417436 (Rhodium: "Wacker with 80% yield in 10min at RT with less Pd", Novel Discourse)
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