AlphaNumeric (Stranger)
06-04-04 12:18
No 511409
      Chromate instead of Dichromate in Oxy synth     

In Lone Ranges synth of Oxycodone here (second synth on the page):
http://rhodium.ws/chemistry/oxycodone2.html
does it matter if Sodium Chromate is used as opposed to the Dichromate salt? I'm not completely familiar with the mechanism for which the Dichromate is needed so I thought I'd better ask.
 
 
 
 
    carbocation
(Stranger)
06-04-04 12:51
No 511414
      Dichromate     

Im not familiar with such synths but I assume that the dichromate is used as an oxidising agent. The dichromate is a stonger oxidising agent than chromate and im not sure if chromate would even work.. remember that it neednt be sodium dichromate- any compound with the dichromate (VI) ion should work.