THF > ClBuOH > ClBuOOH > GHB , Hive Novel Discourse


3base (Newbee) 06-04-02 07:00 No 317495	THF > ClBuOH > ClBuOOH > GHB	Bookmark
	tetrahydrofuran --> 4-chloro-butan-1-ol 4-chloro-butan-1-ol --> 4-chlorobutanoic acid 4-chlorobutanoic acid --> GHB



3base (Newbee) 06-04-02 07:02 No 317497	THF --> 4-chloro-butan-1-ol (Rated as: excellent)	Bookmark
	THF + HCl(g) ,yield 96% THF + HCl(aq),yield 34% (delta-chlorobutanol = 4-chlorobutanol) Patent US2868850 (Patent GB788349, Patent DE1040523) tetrahydrofuran --> 4-chloro-butan-1-ol aqueous hydrochloric acid, tetrachlorosilane additional product: silicic acid tetrakis-(4-chloro-butyl ester) chem listy, 1958 52, 151; kratochvil, frejka chem abstr, 1958, 16329 tetrahydrofuran --> 4-chloro-butan-1-ol hydrochloric acid j amer chem soc, 1934 56, 1596; starr, hixon tetrahydrofuran --> 4-chloro-butan-1-ol hydrochloric acid, temperature 40°C justus liebigs ann chem, 1955 596, 65; reppe et al tetrahydrofuran --> 4-chloro-butan-1-ol HCl, yield 55% liebigs ann chem, 1991 8, 783-788; (english); kenji mori, jiang wu tetrahydrofuran --> 4-chloro-butan-1-ol HCl, bei siedetemperatur book review / secondary ref: org synth coll vol II <1943>571; starr, hixon j amer chem soc, 1934 56, 1596; starr, hixon tetrahydrofuran --> 4-chloro-butan-1-ol HCl(g), yield 57%, heating j org chem ussr, 1987 23, 112-115, (engl transl); a kh khusid zh org khim, 1987 23 1, 126-129; (russian); a kh khusid tetrahydrofuran --> 4-chloro-butan-1-ol HCl gas, temperature 0°C j chem soc perkin trans 1, 1993 17, 2047-2054; (english) leslie crombie, david haigh, raymond c f jones, ab rasid mat-zin, Ab. Rasid tetrahydrofuran --> 4-chloro-butan-1-ol BH2ClSMe2 tetrahedron, 1998 54 31, 8919-8932; (english) Martinez-Bernhardt, Rolando; Castro, Peter P.; Godjoian, Gayane; Gutierrez, Carlos G. tetrahydrofuran --> 4-chloro-butan-1-ol HCl, Solvent H2O, temperature 100°C j org chem, 1998 63 1, 152-162; (english) Pearson, Anthony J.; Gontcharov, Alexander V. Edit:* Retrieved and posted in Post 454558 (Rhodium: "Prep of 4-Chlorobutanol from THF/HCl(aq)", Tryptamine Chemistry) tetrahydrofuran --> 4-chloro-butan-1-ol HCl(gas), heating , 6h, yield 45g chem phys lett, 1999 300 3-4, 493 - 498; (english) Mohan, Hari; Maity, D. K.; Chattopadhyay, S.; Mittal, J. P. tetrahydrofuran --> 4-chloro-butan-1-ol HCl, temperature < 40°C justus liebigs ann chem, 1955 596, 65; reppe et al tetrahydrofuran --> 4-chloro-butan-1-ol HCl collect czech chem commun, 1973 38, 1528-1536; (english); j pola et al bull soc chim fr, 1971, 4341-4350; (french); e brown et al tetrahydrofuran --> 4-chloro-butan-1-ol aq HCl j gen vhem ussr, 1966 36, 1629-1632; (engl transl); d n andreev, g s afanas'eva zh obshch khim, 1966 36, 1628-1633; (russian); d n andreev, g s afanas'eva tetrahydrofuran --> 4-chloro-butan-1-ol (1) AcCl, ZnCl2 (2) MeOH, HCl multistep reaction bull soc chim fr, 1964, 967-972; (french); j huet tetrahydrofuran --> 4-chloro-butan-1-ol HCl gas, heating, 5h, yield 82% j org chem ussr, 1980 16 10, 1728-1733; (engl transl) Kovalev, B. G.; Matveeva, E. D.; Stan, V. V.; Vovk, G. A.; Yudin, L. G.; Kost, A. N. zh org khim, 1980 16 10, 2032-2038; (russian) Kovalev, B. G.; Matveeva, E. D.; Stan, V. V.; Vovk, G. A.; Yudin, L. G.; Kost, A. N. tetrahydrofuran --> 4-chloro-butan-1-ol hydrochloric acid, heating, 8h, yield 45% j org chem, 1981 46 16, 3361-3364 Barry, Carey N.; Evans, Slayton A. Edit: Retrieved and posted in Post 454558 (Rhodium: "Prep of 4-Chlorobutanol from THF/HCl(aq)", Tryptamine Chemistry) Reaction Details 14 of 14 tetrahydrofuran --> 4-chloro-butan-1-ol HCl-gas, 50°C, yield 21% Bouchard, H.; Renard, P. Y.; Lallemand, J. Y. tetrahedron lett, 1991 32 42, 5953-5956, (english)



3base (Newbee) 06-04-02 07:04 No 317498	4-chlorobutanol --> 4-chlorobutanoic acid	Bookmark
	4-chloro-butan-1-ol --> 4-chloro-butyric acid aqueous nitric acid j chem soc, 1952, 4492 4495; crawford, plant 4-chloro-butan-1-ol --> 4-chloro-butyric acid aqueous sulfuric acid, chromium (VI)-oxide j amer chem soc, 1956 78, 2255 2256; pattison et al j org chem, 1956 21, 883 885; pattison et al 4-chloro-butan-1-ol --> 4-chloro-butyric acid indian j chem sect b, 1981 <B> 20 4, 340-342; (english) k k mathew, p s raman, t g antharjanam bhargavi not exactly this rnx, but looks also quite well: butanol + HNO3 --> butanoic acid Patent GB771583



3base (Newbee) 06-04-02 07:05 No 317500	4-chlorobutanoic acid --> GHB	Bookmark
	4-chloro-butyric acid --> 4-hydroxy-butyric acid / butyrolactone temperature 180-200°C die saeure bezw.ihr lacton, das butyrolacton entsteht bull soc chim fr, 1886 <2>45, 341; henry chem zentralbl, 1898 69 II, 273, (german); henry