bottleneck (Hive Bee) 10-01-02 12:40 No 362679				How do you condense a halide with a methyl ester?	Bookmark
						Regarding the SynGen proposed syntheses of lysergic acid from abrine, I presume "E" stands for "ester"? In route G6, they condense 2,3-dihalopropionic acid and a methyl ester. http://syngen2.chem.brandeis.edu/sample-output/lysergic_G6.html For example with methyl acetate, I guess the product should then be 2-(acetoxymethyl)-3-halopropionic acid. Can anyone tell me which reaction would substitute a halo group with the methyl group of a methyl ester in this manner?