pHarmacist (Hive Addict)
04-27-03 14:46
No 429739
      1-(2,5-Dimethoxy-4-(CF3)phenyl)-2-aminopropane  Bookmark   

1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: A Potent Serotonin 5-HT2A/2C Agonist
David E. Nichols, Stewart Frescas, Danuta Marona-Lewicka, Xuemei Huang, Bryan L. Roth, Gary A. Gudelsky, J. Frank Nash;
J. Med. Chem.; 1994; 37(25); 4346-4351.

____ __ _

Full-text: http://pharmacist8.tripod.com/para-CF3.pdf

Accept No Imitations, There Can Only Bee One; www.the-hive.ws
 
 
 
 
    yellium
(I'm Yust a Typo)
04-27-03 15:00
No 429741
      Any plans to synth that compound?  Bookmark   

Any plans to synth that compound?
 
 
 
 
    pHarmacist
(Hive Addict)
04-27-03 15:06
No 429743
      Yes, I'll try to find some time...  Bookmark   

I've got exams now, have no time to even use TFSE sometimes, but I'll try to synth it after this madness. hehe, have fun Yellium... -CF3 function always intrigued me...

Accept No Imitations, There Can Only Bee One; www.the-hive.ws
 
 
 
 
    yellium
(I'm Yust a Typo)
04-27-03 15:29
No 429747
      Post 122784 : Are you sure?  Bookmark   

Post 122784 (dormouse: "Bromo-benzodifuranyl-isopropylamine  -Lilienthal", Serious Chemistry):

Are you sure? 2 weeks to get reasonably 'down' is a long time..
 
 
 
 
    GC_MS
(Hive Addict)
04-27-03 18:20
No 429767
      haha!  Bookmark   

Haha, yeah, two weeks is a long end... wink I have the article here as well, but I regret the use of some expensive chemicals, especially for the trifluoromethylation. I have done some research in the library to find cheaper alternatives, but most searches were in vain. I had some ideas when I was doing the searching, but unless I can find my notes again, I can't give the exact details.
What intrigued me more about this substance was how and why it is that more potent, but also if there have been human trials. I don't know if the information from TFSE is reliable. Two weeks sounds alot. That is about 14 times longer then DOB smile.

The faster you run, the quicker you die.
 
 
 
 
    moo
(Hive Bee)
04-27-03 22:49
No 429810
      I've got the impression that Drone liked to...  Bookmark   

I've got the impression that Drone liked to talk a lot. I'm not saying that I really knew anything about him but on the other hand I don't know how realiable his information on the subject is. Drug folklore is filled with myths, not least because of people who like to boast with them. Maybe it would be wiser to try 2C-TFM first and have a good supply of  downers on hand.

Reading this thread might be worth as well: Post 263890 (poix: "alkylation of quinones", Novel Discourse)
 
 
 
 
    Chimimanie
(Hive Bee)
04-27-03 23:43
No 429818
      I second that  Bookmark   

I really dont think it stay this long, it could not be possible. I have no pharmaceutical knowledge, but I dont trust drone neither.

And yes, lets try 2C-TFM bee4.

Poix has got a good idea in that thread moo, it would bee great if some experimentation could bee done on thiswink.

cool
 
 
 
 
    Rhodium
(Chief Bee)
04-28-03 14:12
No 429967
      2C-TFM  Bookmark   

Rumor has it that 2C-TFM is more stimulating than the 4-halo analogs, and that the duration of action is around 12h. Unfortunately, I have no further details.