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(Stranger) 04-29-04 07:08 No 503744 |
nitroethene adds to indole | |||||||
i once read that nitroethene adds to indole to form ethylnitro indole. refs from dictionary of organic compounds say nitroethene is formed by heating 2-nitro ethanol with some semi-exotic but getable compound to eliminate water. refs say 2-nitro ethanol is in turn formed by reacting nitromethane with formaldehylde. is this method known? if so, can someone provide details on conditions and yield. |
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ning (acetaminophanatic) 04-29-04 08:19 No 503757 |
JOC 1980, 1185 is referenced by ... | |||||||
JOC 1980, 1185 is referenced by ../rhodium/pdf /nichols/nicho where they perform this operation with nitropropenes. It sounds much like a Michael reaction. ../rhodium/pdf /nitroethene.i will have much of what you want to know. In this paper, they used phthalic anhydride to dehydrate the nitroethanol. I imagine almost any anhydride would do. Perhaps even an azeotropic distillation. Who knows? Lastly, you may have been looking for this: ../rhodium/pdf /tryptamine.in have fun. use ye olde search engine. I've been chased by both cops and robbers. So what does that make me? |
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gsus (Hive Bee) 04-29-04 15:13 No 503815 |
2-nitroethanol | |||||||
another method, the formaldehyde/nitromethane way: http://www.orgsyn.org search for 2-nitroethanol. CV 5, 833. with equimolar amts of HCHO and CH3NO2, one gets a 9% yield. large excess nitromethane necessary. http://www.maps.org |
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ning (acetaminophanatic) 04-29-04 20:01 No 503871 |
Ugh! | |||||||
Yes, methinks NaNO2 + ethylene chlorohydrin is definitely the way to go. I've been chased by both cops and robbers. So what does that make me? |
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