trade_om (Stranger)
07-15-04 05:46
No 519570
      4-ho-tryptamine into 4-ho-dmt?     

Hello.
Is going from 4-Hydoxy-Tryptamine into 4-Hydroxy-DiMethylTryptamine possible via any of the routes used to go from tryptamine into dmt? as in this - ../rhodium /tryptamine2dmt.html ?
Or is this completly impossible because the link between the HO molecule and the Carbon is too weak and will break when subjected to this kind of synthesis route?
 
 
 
 
    hest
(Hive Adickt)
07-15-04 06:14
No 519574
      kjiuyh     


4-Hydoxy-Tryptamine into 4-Hydroxy-Tryptamine


huu ???
But yess, iff you have some 4-OH-tryptamine (lucky bastard) you can use the method in the link.

 
 
 
 
    Lego
(Hive Bee)
07-15-04 07:05
No 519581
      They use the benzyl protected 4-OH-indole     

Post 127141 (ejlmp: "Psilocin in 5 steps", Tryptamine Chemistry)

By which method you want to synthesize the 4-hydroxy-indole?

The tendency is to push it as far as you can
 
 
 
 
    trade_om
(Stranger)
07-15-04 08:40
No 519591
      I guess that the one who will choose to follow     

I guess that the one who will choose to follow this reaction would like to purchase the 4-hydroxyindloe from a supplier.
 
 
 
 
    Lego
(Hive Bee)
07-15-04 09:41
No 519599
      Whoops     

Sorry, 4-hydroxy-tryptamine was meant of course....

Purchasing 4-hydroxy-indole/tryptamine is no good idea (in Lego's opinion) for two reasons:
1) the price
2) it is quite suspicious


Try unsubstituted tryptamine first....

The tendency is to push it as far as you can
 
 
 
 
    trade_om
(Stranger)
07-15-04 09:55
No 519602
      I wonder what would be the effects of 6-ho-DMT     

I wonder what would be the effects of 6-ho-DMT if this compound was ever synthesized...
 
 
 
 
    Rhodium
(Chief Bee)
07-15-04 12:33
No 519633
      Hard to focus on one topic at a time, eh? ;-)     


"It is pretty generally accepted that 6-HO-DMT is inactive. I am not too surprised. There are so few things with open and exposed hydroxyl groups that succeed in making it through the lipid barriers to the brain."



Alexander Shulgin in TiHKAL (http://www.erowid.org/library/books_online/tihkal/tihkal03.shtml#6-HO-DMT)


The Hive - Clandestine Chemists Without Borders
 
 
 
 
    Lilienthal
(Moderator)
07-15-04 12:57
No 519638
      Beside that 4-OH-tryptamine is quite ...     

Beside that 4-OH-tryptamine is quite sensitive, especially even under slightly basic conditions. You would want to protect the hydroxy first with an apropriate group.