dwarfer
(esoteric) 05-24-04 10:16 No 509286 |
quinoline-2-carboxylic acids to get you off? | |||||||
Caveney S, Charlet DA, Freitag H, Maier-Stolte M, Starratt AN. For several millennia, stem extracts of Ephedra (Ephedraceae, Gnetales) have been used as folk medicines in both the Old and New World. Some species were used in treatments of questionable efficacy for venereal disease in North America during the last century. Many Eurasian species produce phenylethylamine alkaloids, mostly ephedrine and pseudoephedrine, that interact with adrenergic receptors in the mammalian sympathetic nervous system. Asian Ephedra have been used recently in the clandestine manufacture of a street drug, methamphetamine. are not detectable in New World species of Ephedra, together with Asian species they contain secondary metabolites with known neuropharmacological activity. Many mesic and particularly xeric species worldwide accumulate substantial amounts of or kynurenates, in their aerial parts. Many species of Ephedra accumulate in their stems and roots, and particularly in the seed endosperm. Mesic species synthesize substantial amounts of three rarely seen in nature. A cyclopropyl analogue of proline with known antimicrobial activity, is found in large amounts in the stems and seeds of many Ephedra species. The ability to synthesize cyclopropyl amino acids may be an ancestral feature in the taxon. The natural function in the taxon of these three groups of secondary compounds remains to be established. PMID: 11454619 [PubMed - as supplied by publisher] =================== The chemistry intelligentsia are hereby called upon to identify protocols applicable to the identified alkaloids above, employable by your basic corner lab-tyro, in the conversion of the materials into something that will, you know, like: dwarfer |
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dwarfer (esoteric) 05-25-04 17:00 No 509599 |
Yooby-Hoo | |||||||
Will the CHEMISTRY ELITE please be so kind as to assess quinoline-2-carboxylic acids, cyclopropyl amino acid analogues of glutamate and proline L-2-(carboxycyclopropyl)glycine stereomers and cis-3,4-methanoproline as to their potential?? For I have ZERO knowledge, about this whatsoever, and well.. I mean... what are you FOR?? dwarfer |
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popi (Hive Bee) 05-25-04 17:55 No 509613 |
No doubt it will grow anywhere and get you off | |||||||
This is a good idea for a different source of e.It has been around for long times.Don't knock the potential availability of this product.Get seeds then grow.Same as the myth of Opium Poppy's. They grow everywhere ,but the word used to bee ,'they won't grow here'.Swip has grown a few Persian Whites,Afgan Purple-Whites and ephedra's.This can bee a great cheap source for honey!They are grown now in Austrailia,Canada,Columbia,Mexico and countless other places.Swip will take some seeds and grow.No gak here to worry about!Good info Dwarfer! ssh..the walls have ears and the skys have eyes 'ufa's' |
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Nicodem (Hive Bee) 05-26-04 00:45 No 509702 |
please be so kind as to assess ... | |||||||
please be so kind as to assess quinoline-2-carboxylic acids, cyclopropyl amino acid analogues of glutamate and proline, L-2-(carboxycyclopropyl)glycine stereomers and cis-3,4-methanoproline What exactly do you want to know about these compounds and why do you care about them anyway? If someone would show you the phytochemical composition of lettuce would you ask him to "assess" each of the hundreds chemicals? Ask a more specific question. “The real drug-problem is that we need more and better drugs.” – J. Ott |
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Red_Crown (Newbee) 05-26-04 01:41 No 509707 |
The whole paper.. | |||||||
.. contains some very good information on the chemical composition of various species of Eurasian Ephedra. New Observations on the Secondary Chemistry of World Ephedra (Ephedraceae) Stanley Caveney, David A. Charlet, Helmut Freitag, Maria Maier-Stolte, and Alvin N. Starratt |
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Red_Crown (Newbee) 05-26-04 01:54 No 509709 |
and | |||||||
Dude, Ask Shulgin (http://www.cognitiveliberty.org/shulgin His new book (http://www.cognitiveliberty.org/shulgin |
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Nicodem (Hive Bee) 05-26-04 04:04 No 509718 |
isoquinolines are not quinolines | |||||||
His new book is in the same subject area.. Well, it is not. It is about isoquinolines, especialy tetrahydroisoquinolines. These differ from quinolines by the position of the nitrogen. It is like comparing anilines with benzylamines! “The real drug-problem is that we need more and better drugs.” – J. Ott |
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dwarfer (esoteric) 05-26-04 12:55 No 509777 |
thanks Red-Crown | |||||||
Post 509707 (Red_Crown: "The whole paper..", Stimulants) That's the text for which I could only get the summary, from hich I extracted the info.. ":<) dwarfer |
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dwarfer (esoteric) 05-26-04 13:31 No 509779 |
Parden my termerity | |||||||
Nicodem, I do not think that the matter is so obtuse as to constitute an impenetrable conundrum. Let me guide you through the arcane thought process which gave rise to my question. first of all, we are in the "Stimulants" forum, ya? secondly, alternate sources of precursors to stimulants might be kinda handy, given some of the complaints about the extraactive difficulty of more "regular" sources. Now one of these is ephedra, but as you might note, the reference indicates that NA Ephedra has no ephedra alkaloids, but rather, other psychoactive alkaloids, which were referenced. GThus, then, I enquired about them from some of the more chemically erudite: do the drugs as a class have any potetntial usage for experimentation at the chemhack level.?? Is that a big and stupid question?? Your corellary to lettuce seems a far jump, to me. B ut then, maybe you CAN make opiates from lettuce root? Who knows: I don't. Sems like I recall proline as being a part of synthetic cocaine analogues, but again, I don't know. Kind of a shame if all that millions of hectares of Nevadensis was totally useless.. dwarfer |
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dwarfer (esoteric) 05-26-04 15:37 No 509793 |
carboxylic intermediates | |||||||
gotta be good for something.. <<optimist http://www.interchim.com/interchim/chemi dwarfer |
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Rhodium (Chief Bee) 05-26-04 16:09 No 509801 |
Let's not get out of hand completely here... | |||||||
Yes, everything is good for something, but as there are already so incredibly many things which have proven to be useful for our purposes, please refrain from posting random guesses about "useful things" unless you can reference the reason why you think it could bee a preferable thing to do. The Hive - Clandestine Chemists Without Borders |
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dwarfer (esoteric) 05-28-04 15:11 No 510106 |
why sure | |||||||
Just wishful thinking. one more question, in general. Are there any obvious significant hazards to the bio-absorption of the reduced alkaloids referenced>? dwarfer |
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